Little Known Facts About ceesdekker.
Little Known Facts About ceesdekker.
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Employing solitary-molecule optical and AFM imaging and force-spectroscopy procedures, we search for to unravel the mechanistic facets of the structure and dynamics of chromosomes. Our investigate pursuits incorporate:
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Dynamics of initiation, termination and reinitiation of DNA translocation from the motor protein EcoR124I
Regretably, For a long time just after Iijima’s report, the production of clean nanotubes was cumbersome. In 1996, even so, the team of Richard Smalley at Rice University managed to make single-walled carbon nanotubes at substantial generate. Shortly immediately after, I contacted Smalley, and we decided to be a part of forces to evaluate the transportation through a solitary carbon nanotube.
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Direct immobilization of native yeast iso-1 cytochrome c on bare gold: fast electron relay to redox enzymes and zeptomole protein-film voltammetry
Because 2000 he moved to one-molecule biophysics and nanobiology, with study from DNA supercoiling scientific tests of nucleosomes and DNA fix proteins to DNA translocation as a result of nanopores. Not too long ago his investigate has focused on finding out mobile division with germs on chip, while his final desire is within the course of realizing artificial cells.
He also observed time to jot down several publications, ship Just about forty thousand tweets and guide A prosperous research group at Delft University of Technologies. ‘It doesn’t truly feel like get the job done’, he suggests. ‘I’m just terribly curious.’
Let's say, instead of making use of regular top-down silicon electronics, transistors may be crafted from the bottom up utilizing solitary natural and organic molecules as the switching factors? This concept, which grew to become The premise of today’s area of molecular electronics, 1st emerged in the 1970s.
Bulk-floor coupling identifies the mechanistic link among Min-protein patterns in vivo and in vitro
Because 2000 he moved to one-molecule ceesdekker biophysics and nanobiology, with analysis from studies of DNA loop extrusion and supercoiling to DNA translocation by nanopores. Much more a short while ago his exploration has focused on finding out chromatin structure and mobile division with germs on chip, though he is additionally seeking to eventually Establish synthetic cells from The underside up.
Afterwards we spoke yet again briefly because Dekker felt that our discussion of his faith swiftly grew to become purely philosophical, While it also concretely aids him in his operate.
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes
It was an extremely exciting time, through which I received lots of assistance from Delft University of Engineering, the place I had been a professor at enough time, And that i started off quite a few collaborations with molecular biologists. That served me learn a lot.’